Synonym: conclusive, drastic, endmost, exaggerated, excessive, extravagant, final, last, overdone, radical, terminal. Antonym: moderate, proper, temperate. Similar words: extremely, tremendous, Supreme, remember, retirement, requirement, measurement, next. Meaning: [ɪk'striːm] 
n. 1. the furthest or highest degree of something 2. the point located farthest from the middle of something. adj. 1. of the greatest possible degree or extent or intensity 2. far beyond a norm in quantity or amount or degree; to an utmost degree 3. beyond a norm in views or actions 4. most distant in any direction.
n. 1. the furthest or highest degree of something 2. the point located farthest from the middle of something. adj. 1. of the greatest possible degree or extent or intensity 2. far beyond a norm in quantity or amount or degree; to an utmost degree 3. beyond a norm in views or actions 4. most distant in any direction. 
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211, Sugar addicts gain weight, rot their teeth, and in extreme cases may even develop diabetes.
212, Marsalis scales the stratospheric extreme of the piccolo trumpet without a single bobble.
213, In extreme circumstances the customer or supplier may seek to use its strong position and extract personal benefits in return for giving its consent.
214, The digestion of incisors from mammalian carnivore prey assemblages is more extreme than that of the molars.
215, She even exercises extreme caution about what she throws into her waste-paper bin.
216, Many of the proposals outlined there appear extreme and have not been adopted as policy.
217, In the extreme case where the aggregate supply curve is vertical, the increased money supply will simply lead to higher prices.
218, However, a partner needs gentle handling to tread gently and with extreme caution.
219, The wooden beams and ceiling were crackling in the extreme heat.
220, Providing walkers exercise extreme caution no major problems should be encountered.
221, Extreme care must therefore be taken in the medicinal use of any of these drugs in sufferers from alcoholism.
222, Like the cannon, the diamond anvil is used to mimic the extreme conditions inside the earth.
223, The extreme form of this view, in which there is no role for the state, is labeled anarchism.
224, This perhaps explains the strident colors which characterize his paintings as certainly it suggests the source of their extreme verisimilitude.
225, He was awarded a law degree at the Sorbonne, where he flirted with the extreme right.
226, He was going to have to move with extreme caution.
227, In extreme cases,(http://sentencedict.com/extreme.html) it can affect our whole career progress.
228, Unlike Xenophon, however, Grisone advocated the use of extreme punishment, violence, and brute force.
229, He's had a lifelong fight with feminists who accuse him of extreme male chauvinism and damaging their dignity.
230, This is the big stick treatment for violent criminals which is traditionally associated with an extreme Right-wing attitude.
231, A more extreme development of this pattern is seen in the kestrel, peregrine and buzzard prey assemblages.
232, Extreme surfer and skateboard styles are still a best bet.
233, They discovered that bottleneck after bottleneck arose from extreme specialization within the department.
234, For these and other reasons, it can not be taken as axiomatic that the most extreme threats are the most effective.
235, Also rounding errors can affect cases where extreme accuracy is required.
236, This could include the imposition of sanctions or in extreme circumstances suspension of the client from that establishment.
237, Combining reliable bankable items with the more extreme looks to keep the press happy is no easy matter.
238, In its extreme form, the domain of appropriate state action is reduced to almost nothing, a perspective usually termed libertarianism.
239, The Montegos have been specially adapted to cope with the extreme climate.
240, At the other extreme is the park to which the public has unrestricted access during daylight hours.