Antonym: insignificant. Similar words: significantly, significance, sign in, specifically, esterification, identification, sign on, signal. Meaning: [sɪg'nɪfɪkənt] 
adj. 1. important in effect or meaning 2. fairly large 3. too closely correlated to be attributed to chance and therefore indicating a systematic relation 4. rich in significance or implication.
adj. 1. important in effect or meaning 2. fairly large 3. too closely correlated to be attributed to chance and therefore indicating a systematic relation 4. rich in significance or implication. 
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31. The decision affects a significant proportion of the population.
32. The tax brought about a significant redistribution of wealth.
33. There remained one significant problem.
34. How historically significant is this discovery?
35. The difference in price is not very significant.
36. This decision represents a significant departure from previous policy.
37. They didn't pose a significant risk to safety.
38. Your work has shown a significant improvement.
39. The rise in temperature is not statistically significant.
40. The variation is not statistically significant.
41. These differences are not statistically significant.
42. They have made significant inroads into the European market.
43. Taken together, these factors are highly significant.
44. This development proved highly significant for the whole town.
45. Some of the most significant issues were neglected.
46. She cast him a significant smile.
47. The results of the experiment are not statistically significant.
48. The opinion polls show a significant fall in her popularity.
49. She looked at him across the table and gave him a significant smile.
50. The navy played a limited but significant role in defeating the rebellion.
51. The firm should concede a significant salary increase to its employees.
52. Do you think it's significant that he hasn't replied to my letter yet?
53. The study showed a significant correlation between the baby's sleeping position and the risk of cot death.
54. The moment marked a significant shift in attitudes to the war.
55. Is there any significant difference in quality between these two items?
56. Please inform us if there are any significant changes in your plans.
57. The institution of a Freedom of Information Act has had a significant effect.
58. The difference between the two samples was not statistically significant.
59. It is significant that the writers of the report were all men.
60. There was a significant decline in the size of the business as the company transitioned to an intellectual property company.
More similar words: significantly, significance, sign in, specifically, esterification, identification, sign on, signal, design, resign, assign, terrific, specific, designs, designer, design for, scientific, artificial, signature, assignment, efficacy, uniform, even if, cognitive, magnitude, recognition, sigh, office, campaign, foreigner.