Antonym: insignificant. Similar words: significantly, significance, sign in, specifically, esterification, identification, sign on, signal. Meaning: [sɪg'nɪfɪkənt] 
adj. 1. important in effect or meaning 2. fairly large 3. too closely correlated to be attributed to chance and therefore indicating a systematic relation 4. rich in significance or implication.
adj. 1. important in effect or meaning 2. fairly large 3. too closely correlated to be attributed to chance and therefore indicating a systematic relation 4. rich in significance or implication. 
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61. The accident is already shaping up as a significant environmental disaster.
62. Britain's negotiators had ensured that the treaty which resulted was a significant change in direction.
63. You can look forward to a significant cash return by saving from as little as ￡10 a month.
64. A significant cause of stress in the workplace is a sense of powerlessness and lack of control.
65. As young people started to have more money, a significant youth culture developed.
66. Research in the field of genito-urinary medicine has led to significant health advances in the last decade.
67. As a boxer, his long reach gives him a significant advantage.
68. They have the aircraft capable of doing significant damage, because most of those aircraft are capable of launching anti-ship missiles.
69. There are no significant differences between the two groups of students.
70. A significant number of drivers fail to keep to speed limits.
71. A significant exhibition of contemporary sculpture will be on view at the Portland Gallery.
72. You have all invested significant amounts of time and energy in making this project the success that it is.
73. The new law gives local governments a significant measure of control over their own finances.
74. She suffered a significant loss of hearing after the operation.
75. I haven't noticed any significant reduction in the performance of my car since switching to unleaded fuel.
76. The research is too unfocused to have any significant impact.
77. Do you habitually use display screen equipment as a significant part of your job?
78. Economic factors have played a significant part in Britain's decline as a world power.
79. Police said there had been a significant development in the case.
80. A significant part of Japan's wealth is invested in the West.
81. These views are held by a significant proportion of the population.
82. It was clear that there was significant support for the Islamists.
83. Today's Security Council resolution will be a significant success for American diplomacy.
84. When she died in 1946(sentencedict.com),[http://sentencedict.com/significant.html] her friends wanted to memorialize her in some significant way.
85. The company looks poised to make a significant breakthrough in China.
86. This government has presided over some of the most significant changes in education this century.
87. The mass media have been vested with significant power as social and political agents in modern developed societies.
88. He is seen as having made a significant contribution towards the eradication of corruption.
89. It is significant that he changed his will only days before his death.
90. The talks between the USA and the USSR were very significant for the relationship between the two countries.
More similar words: significantly, significance, sign in, specifically, esterification, identification, sign on, signal, design, resign, assign, terrific, specific, designs, designer, design for, scientific, artificial, signature, assignment, efficacy, uniform, even if, cognitive, magnitude, recognition, sigh, office, campaign, foreigner.