Synonym: bind, fasten, restrain, shackle. Similar words: chair, chairman, wheelchair, maintain, hair, chap., charm, Chart.. Meaning: [tʃeɪn] 
n. 1. a series of things depending on each other as if linked together 2. (chemistry) a series of linked atoms (generally in an organic molecule) 3. a series of (usually metal) rings or links fitted into one another to make a flexible ligament 4. a number of similar establishments (stores or restaurants or banks or hotels or theaters) under one ownership 5. anything that acts as a restraint 6. a unit of length 7. British biochemist (born in Germany) who isolated and purified penicillin, which had been discovered in 1928 by Sir Alexander Fleming (1906-1979) 8. a series of hills or mountains 9. a necklace made by a stringing objects together. v. 1. connect or arrange into a chain by linking 2. fasten or secure with chains.
n. 1. a series of things depending on each other as if linked together 2. (chemistry) a series of linked atoms (generally in an organic molecule) 3. a series of (usually metal) rings or links fitted into one another to make a flexible ligament 4. a number of similar establishments (stores or restaurants or banks or hotels or theaters) under one ownership 5. anything that acts as a restraint 6. a unit of length 7. British biochemist (born in Germany) who isolated and purified penicillin, which had been discovered in 1928 by Sir Alexander Fleming (1906-1979) 8. a series of hills or mountains 9. a necklace made by a stringing objects together. v. 1. connect or arrange into a chain by linking 2. fasten or secure with chains. 
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121. The salesmen are just one link in the chain of distribution.
122. They kept the dog on a chain all day long.
123. When she had an affair with her friend's husband, she wittingly set off a chain of crises.
124. Individualism has been the secret ingredient in developing his chain of fashion stores.
125. As part of the centenary celebrations a chain of beacons was lit across the region.
126. The French company holds a majority stake in the retail chain.
127. She wore a small gold cross on a chain around her neck.
128. The chain of volcanoes is known, appropriately enough, as the 'Ring of Fire'.
129. Put the chain on the door before you go to bed.
130. After twenty years as a chain smoker Mr Nathe has given up the habit.
131. The chain has fretted into the wood and damaged it.
132. The chain has fallen foul of some plants in the water.
133. She sees the bar as a starting point and eventually plans to run her own chain of country inns.
134. She wore a little gold chain around her neck.
135. Traders sitting elbow to elbow formed a human chain.
136. He rode between cars, gripping the heavy chain.
137. Clasp the chain like so.
138. On one ankle she wears a gold chain.
139. At which point she unlocked her ball and chain.
140. The chain saws then started like angry bees.
141. For personal care the chain of complaint is: physician, charge nurse, nursing supervisor, hospital administrator, hospital director.
142. The only true amateurs left are the ones on the bottom end of the highlights-film, commercial-endorsement food chain.
143. You may be surprised to find that she doesn't want to shackle you with a ball and chain.
144. According to their localization, these deletions or duplications frequently provoke major respiratory chain function defects, with consequent cellular energy supply deficiencies.
145. Ruthie had been a budget analyst and then comptroller for a hospital chain for much of her working life.
146. Elizabeth had let him wear a gold chain of hers round his neck.
147. Proteins are asymmetric in an absolute sense in that every copy of the polypeptide chain has the same orientation.
148. Haulage firms would then be allowed to take cattle to abattoirs,[www.Sentencedict.com] with the animals being slaughtered before entering the food chain.
149. To the west of the river a chain of trackways and paths provide a more appealing route.
150. Loyalty to a petrified opinion never yet broke a chain or freed a human soul. Mark Twain 