Synonym: conundrum, enigma, issue, mystery, perplexity, puzzle, question. Antonym: solution. Similar words: probably, robot, oblivious, obligation, lemon, element, dilemma, implement. Meaning: ['prɑbləm /'prɒ-] 
n. 1. a state of difficulty that needs to be resolved 2. a source of difficulty 3. a question raised for consideration or solution.
n. 1. a state of difficulty that needs to be resolved 2. a source of difficulty 3. a question raised for consideration or solution. 
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241 The problem is paying the mortgage-everything else is liveable with.
242 The professor is never at a nonplus, and never perplexed by a problem.
243 It is impossible to predetermine every specific problem that we will meet.
244 This is one possible solution to the problem. However, there are others.
245 The problem is not their lack of funding, but rather their lack of planning.
246 I do not want drugs in this school. It's essential that we nip the problem in the bud so I want a meeting with all the parents next week.
247 They will change their tune when they find out the seriousness of the problem.
248 The problem was how to say 'no' to her without causing offence.
249 Ninety-nine times out of a hundred everything's fine, but now and then there's a problem.
250 This problem should be easy enough for someone who's done physics at A level.
251 That depends ( on ) how to tackle the problem.
251 Wish you will love sentencedict.com and make progress everyday!
252 To see the problem here more clearly, let's look at a different biological system, say, an acorn.
253 Tom's problem was that he lacked confidence; Ed failed for precisely the opposite reason.
254 We must take positive steps to deal with the problem.
255 Your problem with keeping boyfriends is just a symptom of a larger problem: making and keeping friends.
256 I've gone over the problem several times, but I can't think of a solution.
257 What do you think is the nub of the problem?
258 Your problem is that you take your wife for granted.When was the last time you told her how much you appreciated her?
259 My doctor said the problem was more emotional than physical.
260 One moment the professor is working hard on a problem in physics[sentencedict.com], the next he's gone off at a tangent and he's talking about bees.
261 We need time to inform ourselves thoroughly of the problem.
262 Do you see a way of getting round the problem?
263 No-one likes conflict, but at the same time we have to deal with this problem.
264 As likely as not, she'll end up in court over this problem.
265 The points you make are true, but they're incidental to the main problem.
266 The last problem is to reduce an equation to its simplest form.
267 To trace the origins of the Irish problem, we have to go back over three hundred years.
268 Neither the teacher nor his students know how to work out the problem.
More similar words: probably, robot, oblivious, obligation, lemon, element, dilemma, implement, settlement, elementary, finite element, implementation, pro, able, table, cable, bless, blend, Bible, bubble, enable, unable, marble, double, foible, prompt, be able to, visible, voluble, stumble.