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(1) Riligion converts despair, which destroys, into resignation, which submits. 

(2) Despair gives courage to a coward. 

(3) He who has never hoped can never despair. 

(4) Our destiny offers not the cup of despair, but the chalice of opportunity. 

(5) This poem communicates the author's despair.

(6) He soon gave up the attempt in despair.

(7) Despair doubled expect change twice.

(8) They're in despair over/about the money they've lost.

(9) She uttered a wordless cry of despair.

(10) Defeat after defeat filled us with despair.

(11) He gave up the struggle in despair.

(12) I despair at the policies of this govenment.

(13) He is plunging into an abyss of despair.

(14) He threw up his hands in despair.

(15) I looked at my wife in despair.

(16) I despair of you[sentencedict .com], Ian — act your age!

(17) In despair, the young boy had hanged himself.

(18) She killed herself in despair.

(19) Euphoria soon gave way to despair.

(20) Tiredness and despair were etched into his face.

(21) He is the despair of all other pianists.

(22) Bergman's films are often full of gloom and despair.

(23) A deep sense of despair overwhelmed him.

(24) Life begins on the other side of despair.

(25) She alternated between cheerfulness and deep despair.

(26) He was in the depths of despair/depression about losing his job.

(27) The book describes a spiritual journey from despair to happiness.

(28) A low moan of despair escaped her as she realized what had gone wrong.

(29) The most glorious moment in your life are not the socalled days of success, but rather those days when out of dejection and despair you feel rise in you a challenge to life, and the promise of future accomplishment. 

(30) In all things, it is better to hope than to despair. 

(1) He soon gave up the attempt in despair.

(2) They're in despair over/about the money they've lost.

(3) She uttered a wordless cry of despair.

(4) Defeat after defeat filled us with despair.

(5) He gave up the struggle in despair.

(6) I despair at the policies of this govenment.

(7) He is plunging into an abyss of despair.

(8) He threw up his hands in despair.

(9) I looked at my wife in despair.

(10) I despair of you, Ian — act your age!

(11) In despair, the young boy had hanged himself.

(12) She killed herself in despair.

(13) Euphoria soon gave way to despair.

(14) Tiredness and despair were etched into his face.

(15) He is the despair of all other pianists.

(16) Bergman's films are often full of gloom and despair.

(17) A deep sense of despair overwhelmed him.

(18) She alternated between cheerfulness and deep despair.

(19) He was in the depths of despair/depression about losing his job.

(20) The book describes a spiritual journey from despair to happiness.

(21) A low moan of despair escaped her as she realized what had gone wrong.

(22) One harsh word would send her into the depths of despair.

(23) His mind seesawed between hope and despair all through those weeks.

(24) When his wife left him, Matt plumbed the very depths of despair.

(25) Eventually, driven to despair, he threw himself under a train.

(26) The novel tells the story of a teenager driven to despair by the hypocrisy of the adult world.

(27) Never despair of success.

(28) She finished what she had to say with a gesture of despair.

(29) He was in utter despair.

(30) The rejection plunged her into the dark depths of despair.