Synonym: ache, discomfort, distress, hurt, irritation, pang, soreness, suffering. Antonym: pleasure, relieve. Similar words: painter, paintwork, maintain, pair, impair, repair, a pair of, campaign. Meaning: [peɪn] 
n. 1. a symptom of some physical hurt or disorder 2. emotional distress; a fundamental feeling that people try to avoid 3. a somatic sensation of acute discomfort 4. a bothersome annoying person 5. something or someone that causes trouble; a source of unhappiness. v. 1. cause bodily suffering to and make sick or indisposed 2. cause emotional anguish or make miserable.
n. 1. a symptom of some physical hurt or disorder 2. emotional distress; a fundamental feeling that people try to avoid 3. a somatic sensation of acute discomfort 4. a bothersome annoying person 5. something or someone that causes trouble; a source of unhappiness. v. 1. cause bodily suffering to and make sick or indisposed 2. cause emotional anguish or make miserable. 
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1. Knowledge will not be aquired without pain and application. 
2. Poverty is a pain, but no disgrace.
3. Pain is forgotten where gain follows.
4. When the wound is healed, the pain is forgotten.
5. It is more pain to do nothing than something.
6. Every pleasure has a pain.
7. No man learns but by pain or shame.
8. No pleasure without alloy (or pain or repentance).
9. There is no pleasure without pain.
10. He pain of the mind is worse than the pain of the body.
11. The pain of the mind is worse than the pain of the body.
12. No man can be brave who considers pain the greatest evil of life; or temperate,[sentencedict.com] who regards pleasure as the highest good.
13. Take a pain for a pleasure all wise men can.
14. Riches are gotten with pain, kept with care, and lost with grief.
15. No pain, no gain.
16. A certain amount of care or pain or trouble is necessary for every man at all times.A ship without a ballast is unstable and will not go straight.
17. No pain, no palm; no thorns, no throne; no gall, no glory; no cross, no crown.
18. No pleasure without pain.
19. The pain was almost too great to endure.
20. The constant pain made her life intolerable.
21. The wounded soldier lashed around in great pain.
22. Without pain, without sacrifice, we would have nothing.
23. The patient's face twisted up with pain.
24. The tablets brought temporary respite from the excruciating pain.
25. The pain in her jaw had come back.
26. The spider's bite can cause pain and swelling.
27. He moaned with pain before losing consciousness.
28. When I bend my arm, the pain is excruciating.
29. She was in constant physical pain.
30. The booklet contains information on pain relief during labour.