Synonym: fail, flop, forfeit, mislay, misplace, sacrifice. Antonym: find, gain, win. Similar words: close, closet, closer, closest, closely, close in, close up, close down. Meaning: [luːz] 
v. 1. fail to keep or to maintain; cease to have, either physically or in an abstract sense 2. fail to win 3. suffer the loss of a person through death or removal 4. place (something) where one cannot find it again 5. miss from one's possessions; lose sight of 6. allow to go out of sight 7. fail to make money in a business; make a loss or fail to profit 8. fail to get or obtain 9. retreat 10. fail to perceive or to catch with the senses or the mind 11. be set at a disadvantage.
v. 1. fail to keep or to maintain; cease to have, either physically or in an abstract sense 2. fail to win 3. suffer the loss of a person through death or removal 4. place (something) where one cannot find it again 5. miss from one's possessions; lose sight of 6. allow to go out of sight 7. fail to make money in a business; make a loss or fail to profit 8. fail to get or obtain 9. retreat 10. fail to perceive or to catch with the senses or the mind 11. be set at a disadvantage. 
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151. Don't lose your reason however excited you are.
152. We must not lose sight of our original aim.
153. Most trees lose their foliage in winter.
154. Let us not lose touch with reality.
155. I've got to lose this flab on my belly!
156. She'd rather die than lose the children.
157. She doesn't want to lose her hard-won independence.
158. Win or lose, I love competitive sports.
159. You have nothing to lose by telling the truth.
160. In the end they lose millions, perhaps billions.
161. The blow caused him to lose consciousness.
162. Sherry's been making a strenuous effort to lose weight.
163. I'm beginning to lose patience with you people.
164. Pin the bills together so you don't lose them.
165. You will lose nothing by telling the truth.
166. He was unlucky enough to lose his keys.
167. Without continued learning,[sentencedict.com] graduates will lose their intellectual vitality.
168. He's afraid of losing customers/that he might lose customers.
169. The business will lose money if it doesn't modernize.
170. We mustn't lose heart when people complain.
171. For each mistake, you'll lose half a point.
172. They worried that German companies would lose business.
173. It's hard to see how they can lose.
174. You'll lose your fellowship if you do that.
175. It signs that he will lose his temper.
176. He vowed he would lose weight.
177. Mr Eyer may lose the sight in one eye.
178. I wouldn't lose any sleep over what happened.
179. He began to lose his sight six years ago.
180. 'We're going to lose.' 'Not necessarily.'