Synonym: earnest, engrossed, grave, important, momentous, pensive, profound, reflective, sincere, solemn, thoughtful, weighty, zealous. Antonym: frivolous. Similar words: imperious, mysterious, curious, various, furious, notorious, nefarious, glorious. Meaning: ['sɪrɪəs /'sɪər-] 
adj. 1. concerned with work or important matters rather than play or trivialities 2. of great consequence 3. causing fear or anxiety by threatening great harm 4. appealing to the mind 5. completely lacking in playfulness 6. requiring effort or concentration; complex and not easy to answer or solve.
adj. 1. concerned with work or important matters rather than play or trivialities 2. of great consequence 3. causing fear or anxiety by threatening great harm 4. appealing to the mind 5. completely lacking in playfulness 6. requiring effort or concentration; complex and not easy to answer or solve. 
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91. Drug - smuggling is a serious crime.
92. Widespread protests have placed the President under serious pressure.
93. This trifle developed itself into a serious problem.
94. I developed serious arthritic symptoms and chronic sinusitis.
95. Malaria is a kind of serious malady.
96. We were put at a serious disadvantage.
97. Dr Lee was cleared of serious professional misconduct.
98. The allegations are serious enough to warrant an investigation.
99. Keep some blood plasma back for the serious cases.
100. His face is serious but nonetheless very friendly.
101. The stability of affairs is very serious.
102. The small argument boiled over into a serious quarrel.
103. He is currently on trial accused of serious drugs charges.
104. This is actually a very entertaining book putting over serious health messages.
105. Don't quote me on this, but I think the company is in serious difficulties.
106. The voice at the other end of the line was serious and commanding.
107. She was fitted with a pacemaker after suffering serious heart trouble.
108. Stuart got serious quickly and popped the question six months later.
109. The current trade deficit indicates a serious imbalance between our import and export trade.
110. He was gifted, on occasion, with a gentle raillery, which almost always concealed a serious meaning.
111. Smoking places you at serious risk of cardiovascular and respiratory disease.
112. People don't realize how serious this recession has actually been.
113. The incident was being seen as a serious security lapse.
113. Sentencedict.com is a online sentence dictionary, on which you can find nice sentences for a large number of words.
114. There is a danger of serious contamination from radioactive waste.
115. He was a consultant physician, a serious man dedicated to his calling.
116. They will consider whether or not he has been guilty of serious professional misconduct.
117. Their actions threatened a serious breach in relations between the two countries.
118. Make sure that your immunisations are up to date to lessen the risk of serious illness.
119. A third presidential candidate emerged to mount a serious challenge and throw the campaign wide open.
120. There have been many attempts, both light-hearted and serious, to locate the Loch Ness Monster.
More similar words: imperious, mysterious, curious, various, furious, notorious, nefarious, glorious, delirious, penurious, gregarious, notoriously, precarious, lugubrious, laboriously, glorious revolution, period, series, superior, inferior, ulterior, interior, exterior, a series of, deteriorate, riotous, pious, odious, perilous, envious.