Synonym: conduct, direct, escort, guide, head, run. Similar words: plead, leader, lead to, leading, lead up to, take the lead, leadership, lean. Meaning: [lɪːd] 
n. 1. a soft heavy toxic malleable metallic element; bluish white when freshly cut but tarnishes readily to dull grey 2. an advantage held by a competitor in a race 3. evidence pointing to a possible solution 4. a position of leadership (especially in the phrase `take the lead') 5. the angle between the direction a gun is aimed and the position of a moving target (correcting for the flight time of the missile) 6. the introductory section of a story 7. (sports) the score by which a team or individual is winning 8. an actor who plays a principal role 9. (baseball) the position taken by a base runner preparing to advance to the next base 10. an indication of potential opportunity 11. a news story of major importance 12. the timing of ignition relative to the position of the piston in an internal-combustion engine 13. restraint consisting of a rope (or light chain) used to restrain an animal 14. thin strip of metal used to separate lines of type in printing 15. mixture of graphite with clay in different degrees of hardness; the marking substance in a pencil 16. a jumper that consists of a short piece of wire 17. the playing of a card to start a trick in bridge. v. 1. take somebody somewhere 2. have as a result or residue 3. tend to or result in 4. travel in front of; go in advance of others 5. cause to undertake a certain action 6. stretch out over a distance, space, time, or scope; run or extend between two points or beyond a certain point 7. be in charge of 8. be ahead of others; be the first 9. be conducive to 10. lead, as in the performance of a composition 11. pass or spend 12. lead, extend, or afford access 13. move ahead (of others) in time or space 14. cause something to pass or lead somewhere 15. preside over.
n. 1. a soft heavy toxic malleable metallic element; bluish white when freshly cut but tarnishes readily to dull grey 2. an advantage held by a competitor in a race 3. evidence pointing to a possible solution 4. a position of leadership (especially in the phrase `take the lead') 5. the angle between the direction a gun is aimed and the position of a moving target (correcting for the flight time of the missile) 6. the introductory section of a story 7. (sports) the score by which a team or individual is winning 8. an actor who plays a principal role 9. (baseball) the position taken by a base runner preparing to advance to the next base 10. an indication of potential opportunity 11. a news story of major importance 12. the timing of ignition relative to the position of the piston in an internal-combustion engine 13. restraint consisting of a rope (or light chain) used to restrain an animal 14. thin strip of metal used to separate lines of type in printing 15. mixture of graphite with clay in different degrees of hardness; the marking substance in a pencil 16. a jumper that consists of a short piece of wire 17. the playing of a card to start a trick in bridge. v. 1. take somebody somewhere 2. have as a result or residue 3. tend to or result in 4. travel in front of; go in advance of others 5. cause to undertake a certain action 6. stretch out over a distance, space, time, or scope; run or extend between two points or beyond a certain point 7. be in charge of 8. be ahead of others; be the first 9. be conducive to 10. lead, as in the performance of a composition 11. pass or spend 12. lead, extend, or afford access 13. move ahead (of others) in time or space 14. cause something to pass or lead somewhere 15. preside over. 
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271 Her big break came when she was chosen to play the lead in a Broadway musical.
272 Greater spending on education is expected to lead to a large increase in the number of students.
273 The original white lead pigments have oxidized and turned black.
274 Many factors can lead to growth retardation in unborn babies.
275 A degree in English could lead to a career in journalism.
276 Please keep your dog on a lead when on the beach.
277 Worrying about your weight is more likely to lead to comforting yourself with a piece of chocolate.
278 They lead a busy and colourful life on the campus.
279 Reducing speed limits should lead to fewer deaths on the roads.
280 Do you know if a piece of lead will weigh down an equal bulk of iron?
281 Over half of all children in Britain get glue ear at some time before they are 16[sentencedict.com], and it can lead to permanent hearing loss.
282 I was half a mile in the lead burning the earth like a gust of wind.