Synonym: boastful, conceited, egocentric, egotistical, fruitless, futile, haughty, ineffectual, lofty, proud, self-centered, unsuccessful. Antonym: effective, effectual. Similar words: in vain, maintain, prevail, available, be available, availability, pain, ain't. Meaning: [veɪn] 
adj. 1. characteristic of false pride; having an exaggerated sense of self-importance 2. unproductive of success.
adj. 1. characteristic of false pride; having an exaggerated sense of self-importance 2. unproductive of success. 
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121. Workers tried in vain to keep the building from collapsing.
122. I suppose that might be a fear of being considered big-headed or vain.
123. Before the offensive began he had tried in vain to impress this upon his superiors.
124. The eternal quest for immortality will be in vain until we know the answer - unfortunately, we don't.
125. Jane thinks that they will probably marry in actuality but that he can not love the vain, shallow woman.
126. In a vain attempt to maintain her independence, she spent Monday and Tuesday nights at home - alone.
127. Those dealing with heart disease have looked for such clean-cut results in vain. Sentencedict.com
128. Vanity and pride are different things, though the words are often used synonymously. A person may be proud without being vain. Pride relates more to our opinion of ourselves; vanity, to what we would have others think of us. Jane Austen 
129. He wraps around himself the dusty patchwork cloak of his invisibility and the heralds gallop hither and yon in vain.
130. If people don't learn from this, then his suffering and death were in vain.
131. The court heard a harrowing 999 tape of the boy, then 10, as he tried in vain to stop the killing.
132. In 1562 and again in 1566 the Privy Council urged Elizabeth in vain to marry and secure the succession.
133. Many princes and rich men try in vain to amuse her.
134. How vain it is to sit down to write when you have not stood up to live. Henry David Thoreau
135. In vain he hoped to carve out an alternative career as a journalist and cricket writer.
136. Once, I dived full-length across the court in a vain attempt to retrieve the ball.
137. One looks in vain for any evidence of soul-searching among the legal clan.
138. He stretched up his arms in a vain effort to reach the top of the embankment.
139. Children, also, carrying their bundles and striving in vain to keep up with their seniors.
140. It would be naive and vain to try to emulate Pope John, who was unique and unrepeatable.
141. Rain and pain never go in vain! They are just tests before we see gain. RVM
142. Mum Cheryl needs a heart-lung transplant but she has been waiting in vain for a donor since January.
143. She's a vain girl who is always thinking about her figure.
144. At least my friend didn't think I was vain enough to commission the work myself.
145. In the last months of 1978 several of his former servants were arrested in this vain hope.
146. The vision of the vain, silly girl she had been seemed to accuse her in some obscure way.
147. Historians win look in vain for a revealing memo, an angry note.
148. They looked in vain for a nook that held the batteries.
149. Those who set the monstrosity of globalisation in train seek in vain to dissociate themselves from the effects of their actions.
150. But city girls wait in vain for theirs to grow big and sexy.