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1. Both the phosphorylation of receptors and their absence means that it takes more of the drug to obtain the same effect.
2. During phosphorylation, the active-centre torsion-angle strain should facilitate the phosphotransfer reaction by lowering the activation-energy barrier.
3. Phosphorylation of myosin promotes its binding to F-actin.
4. Finally, oxidative phosphorylation itself can also harm the cell.
5. It is demonstrated that phosphorylation and dephosphorylation of NRs play a critical role in a variety of signaling pathways.
6. The phosphorylation of STAT5 and its location were examined by double immunohistochemical staining and the binding of STAT5 with DNA was determined by electrophoretic mobility shift assay (EMSA).
7. The regulatory step affected by phosphorylation could involve either recognition of the substrate by an E3 ubiquitin ligase or the actual conjugation reaction.
8. Enzyme is used to make glucose or saccharose phosphorylation to prepare FDP. Purified FDP is extracted by sedimentation, transformation, ion absorption, cleaning and crystallization.
9. The reversible phosphorylation of proteins is important in intercellular communication.
10. The tyrosine phosphorylation of leptin receptor was revealed by immuno precipitation.
11. The tyrosine phosphorylation of IRS-1 was measured by immunoprecipitation and enhanced chemiluminescent immunoblotting technique.
12. Zidovudine may competitively inhibit the intracellular phosphorylation of stavudine. Therefore[sentencedict.com], use of zidovudine in combination with Stavudine is not recommended.
13. Until now there have been few reports on hepatic failure caused by disorders of mitochondrial oxidative phosphorylation.
14. The necessity for using very high doses of reagents, however, to detect invitro phosphorylation of membranes, is well recognised.
15. This torsion-angle strain would lower the activation-energy barrier for the phosphorylation of His15.
16. The mechanism of action was proved to be reversible phosphorylation and dephosphorylation.
17. Subsequently, we monitored the ligand-dependent HER profiles based on receptor expression, phosphorylation, and dimerization in conjunction with measurements of cellular susceptibility to gefitinib.
18. We think that spleen governing transportation and transformation is not merely gastrointestinal digestion and absorption of food, most important is the mitochondria oxidative phosphorylation.
19. Conclusion: Our study indicates that JAK kinase can affect the activity of ERK signal transduction pathway through the phosphorylation of ERK.
20. More investigations are required for understanding mechanisms of the phosphorylation -induced stabilization of nucleolin molecules.
21. Changes in the distribution of light energy in photosystem and the phosphorylation of the thylakoid membrane proteins in rice leaves (Oryza sativa L. ) during chilling stress were studied.
22. Results After hypoxia, the contractile response of VSMC to NE was significantly decreased. Meanwhile the level of MLC20 phosphorylation and calcium sensitivity of SMA after shock were decreased.
23. By way of immunoprecipitation and immunoblotting, the cytosolic protein tyrosine phosphorylation was examined.
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24. Genistein, the tyrosine kinase inhibitors, plays the effect by an inhibition of tyrosine phosphorylation.
25. CONCLUSION SAB and Curcumin could significantly inhibit the proliferation, activation and ERK phosphorylation.
26. On page 1682, Holt et al. (2) show that most phosphorylation sites shift position in rapidly evolving, disordered regions of proteins.
27. Mutations of human mitochondrial DNA may lead to aberrant oxidative phosphorylation and energy supplement in cells, indicating a possible relationship with bipolar disorder.
28. Leigh syndrome is a severe early - onset progressive neurodegenerative disorder due to mitochondrial oxidative phosphorylation defects.
29. The team showed that CDK1 short-circuits EZH2-mediated methylation by attaching a different chemical group consisting of one phosphate and three oxygen atoms to EZH2, a process called phosphorylation.
30. In this study, phosphoramide mustard was coupled to 2-phenyl-4-quinolone by a facile phosphorylation reaction to yield a novel quinoline-4-phosphoramidate derivative.
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