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31. In one study, the half-life of caffeine in premature infants ranged from 41 to 231 hours.

32. Unlike caffeine, these molecules have only two methyl groups attached to their xanthine skeleton.

33. Under the influence of a pint of caffeine the world seemed a friendlier place.

34. Women who nurse their infants need to be careful as well because babies lack the liver enzymes needed to break down caffeine.

35. On the Rebound Since caffeine is relatively inexpensive and widely available, the dose escalation induced by tolerance is seldom burdensome.

36. As cocoa contains caffeine, it would have stimulated the Temperance workers on their way.

37. In many ways, caffeine is in a different league from other recreational drugs.

38. But both of these contain caffeine and other chemical stimulants which are quickly absorbed into the bloodstream.

39. When caffeine blocks these receptors, blood vessels dilate, increasing the filtration rate and producing more urine.

40. But as a headache remedy, caffeine can be tricky to manage.

41. Obvious examples include caffeine and ephedrine, the latter being readily available to the public in over-the-counter cold remedies.

42. Theophylline is roughly as potent as caffeine; theobromine is seven times weaker than either.

43. And yet, despite its safety and mildness relative to other recreational drugs, caffeine still unquestionably alters brain function.

44. Progress in learning how alcohol and caffeine work has had to wait for new knowledge of how the brain works.

45. But unlike the action in the kidney, where caffeine causes a dilation, in the colon it causes a constriction.

46. The standard dose of alcohol is thus roughly 142 times larger than the standard dose of caffeine.

47. In any case, the current legal limits for caffeine are sufficiently high to allow a wide latitude of experimentation.

48. Yes, especially the spice and green teas-and they managed it without the caffeine too.

49. Out of ninety-nine people screened for the study, sixteen were diagnosed as caffeine dependent after undergoing a battery of evaluations.

50. She needed the hot draught of caffeine to clear her head.

51. But only in the past several years have neuroscientists made much progress in illuminating how caffeine revs up the brain.

52. Caffeine also directly affects many parts of the body by attaching to adenosine receptors found outside the brain.

53. Some of the new findings, though, support previously unsubstantiated folk wisdom about alcohol and caffeine.

54. Since caffeine is usually consumed in beverages, the liquid by itself will result in an increased urge to urinate.

55. How is it, then, that caffeine is found in plants as unrelated as certain species of lilies and cacti?

56. Many brands of aspirin and aspirin substitutes include a significant dose of caffeine.

57. It was only after the caffeine began to work that he realized that everyone was kind of waiting for something to happen.

58. These results suggest that caffeine indirectly affects many neurotransmitter systems through its direct effects on adenosine receptors.

59. In the United States,[Sentencedict.com] alcohol is second only to caffeine as the drug of choice.

60. In short, recent scientific progress has revolutionized the understanding of alcohol and caffeine.