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(1) Setting the stage in colorectal cancer?

(2) An altered glycosylation phenotype in colorectal cancer.

(3) The strong association between colorectal dysplasia and cancer in ulcerative colitis was described in 1967.

(4) The specific carcinogens, however, that cause the colorectal cancers in humans remain unknown.

(5) Each set of sections included a positive colorectal carcinoma control, and a negative control in which the primary antibody was omitted.

(6) The proliferation of the colorectal lines was unaffected by histamine.

(7) The potential autocrine grown effects of gastrin in colorectal cancer have previously been studied using cell lines.

(8) The presence of other chromosomal deletions in colorectal cancer suggests that several more tumour suppressor genes have yet to be identified.

(9) Simple indicators of colorectal carcinoma would help to rationalise and improve the efficiency of the investigation of iron deficiency anaemia.

(10) Calcium may protect against colorectal cancer by reducing epithelial cell turnover.

(11) Patients with established colorectal cancer showed increased proportions of secondary bile acids in their faeces.

(12) Patients with colorectal cancer are reported to have postprandial hypergastrinaemia which returns to normal after tumour resection.

(13) Research into colorectal tumours has directly or indirectly contributed to the discovery of three new tumour suppressor genes.

(14) All but one of the colorectal cancers in this series occurred in patients outside the surveillance programme.

(15) While the evidence linking increased cell proliferation and colorectal cancer is good, the converse is less clear cut.

(16) The prospective study, however, indicated a clear cut association between pseudomelanosis coli and colorectal tumours in man.

(17) Tumour suppressor genes seem to be very important in colorectal carcinogenesis.

(18) Differences in the glycosylation of cell surface components of colorectal cancer cells have been previously shown.

(19) Deletions of chromosome 17p are found in 75% of colorectal cancers and are highly correlated with mutation of the remaining p53 gene.

(20) In addition, the distribution of characteristics known to affect survival in colorectal cancer was similar in the two study groups.

(21) This would greatly facilitate the treatment of genetically complex tumours like colorectal cancer. Sentencedict.com

(22) Other studies have failed to show a relation between serum cholesterol and colorectal carcinoma.

(23) In this study we have examined both benign and malignant colorectal strictures in ulcerative colitis and have compared their features.

(24) Few studies have been carried out assessing the effect of vitamin supplementation on adenomatous polyps or colorectal cancer.

(25) We have now shown an invitro physiological response in colorectal tissue to the active metabolite of vitamin D 3 and related compounds.

(26) Invasion and metastasis largely determine the clinical course of colorectal carcinomas.

(27) Other workers have found ras gene mutations in between 39% and 47% of colorectal cancers.

(28) The relative complexity of gastric crypt anatomy compared with colorectal mucosa has discouraged its use as an experimental model in proliferation research.

(29) It has been previously shown that the expression of integrins is differently diminished in a chain-specific manner in human colorectal cancer.

(30) This suggests that such indices are unlikely to provide useful markers for the identification of colorectal cancer risk as previously proposed.