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1. The beetle contains a caustic acid-like juice called cantharidin.
2. Cantharidin can lighten symptom of hepatic carcinoma and debase the content of AFP.
3. A method for separation and determination of cantharidin from the culture of medicinal fungi using capillary gas chromatography was developed.
4. The bound cantharidin may exist in the forms of magnesium cantharidate and calcium cantharidate.
5. Objective To investigate the inhibition effect of cantharidin on the proliferation of human being carcinoma A549 cell.
6. Aims To study the influence of cantharidin on the proliferation of xenografts of human pancreatic cancer cell sw1990 in nude mice.
7. Conclusions Cantharidin has the inhibition effect to the proliferation of human being carcinoma A549 cell.
8. Cantharidin, a terpenoid substance, is contained in a group of widely spreading insects—the blister beetles (Coleoptera: Meloidae) in the world.
9. The only problem is that cantharidin is toxic, and the victims are usually women who unwittingly consume the powder in a drink.
10. Results of quantitative measurement of cantharidin by GC using aprobarhital as an internal standard were reliable.
11. The invention relates to the field of cantharidin derivate and successfully synthetizes the norcantharidin dimer derivate by using ethylene diamine as a connecting arm.
12. Results Cantharidin inhibited the proliferation of A549 cell, and the mechanism of inhibitory action is to make A549 cell cycle hindered at G2/M.
13. These procedures were applied to study the postmortem distribution of cantharidin in poisoned animals.
14. We select high quality raw materials to produce animal and plant extraction such as Cantharidin, Tea polyphenols, ect.
15. Methods MTT assay was used to determine the proliferation inhibition by cantharidin to A549 cell.
16. The mixture of chloroform and anisole is used to replace chloroform or acetone with better results in cantharidin abstraction efficiency and reappearance.
17. The volume of the chemical may vary depending on the sex, age, mating records and feeding conditions. The cantharidin measure can reach as high as 10% in some sexually matured male beetles.
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18. Though there are some research reports, no final conclusions about biosynthesis pathway of cantharidin and its distribution in the body of meloid have been achieved yet.
19. And the mol of Ca element in Mylabris was lower than that of the bound cantharidin.
20. CONCLUSION:MAPK signal transduction pathway participates the proliferation inhibition of cantharidin on A549 cell.
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