Similar words: ragout, drag out, cagoule, gout, gourd, go up, log out, vigour. Meaning: n. agile long-legged rabbit-sized rodent of Central America and South America and the West Indies; valued as food.
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1. If the agouti finds one, it is likely to find far more than it can eat at a single sitting.
2. Typically, when agouti mice breed, most of the offspring are identical to the parents: just as yellow, fat as pincushions, and susceptible to life-shortening disease.
3. Jirtle's team fed one group of pregnant agouti mice a diet rich in B vitamins (folic acid and vitamin B12). Another group of genetically identical pregnant agouti mice got no such prenatal nutrition.
4. After being consumed by the mothers, the methyl donors worked their way into the developing embryos' chromosomes and onto the critical agouti gene.
5. The B vitamins acted as methyl donors: they caused methyl groups to attach more frequently to the agouti gene in utero, thereby altering its expression.
6. The most well known example is that of the Agouti mice: they are yellow, fat and are prone to diabetes and cancer.